Papers
Papers from the Bloom Lab team. See also Google Scholar for a complete list of publications.
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Key Papers
These papers exemplify key current areas of research in the lab.
High-throughput sequencing-based neutralization assay reveals how repeated vaccinations impact titers to recent human H1N1 influenza strains
Journal of Virology. 2024Deep mutational scanning reveals functional constraints and antibody-escape potential of Lassa virus glycoprotein complex
Immunity. 2024Full-spike deep mutational scanning helps predict the evolutionary success of SARS-CoV-2 clades
Nature. 2024All Papers
Below is a complete list of primary research papers from our group.
dms-viz: Structure-informed visualizations for deep mutational scanning and other mutation-based datasets
Journal of Open Source Software. 2024. doi:10.21105/joss.06129Fitness effects of mutations to SARS-CoV-2 proteins
Virus Evolution. 2023. doi:10.1093/ve/veae026Evolution of the SARS-CoV-2 mutational spectrum
Molecular Biology and Evolution. 2023. doi:10.1093/molbev/msad085Dynamics of neutralizing antibody titers in the months after severe acute respiratory syndrome coronavirus 2 infection
The Journal of infectious diseases. 2021. doi:10.1093/infdis/jiaa618When two are better than one: Modeling the mechanisms of antibody mixtures
PLoS computational biology. 2020. doi:10.1371/journal.pcbi.1007830Within-host evolution of human influenza virus
Trends in Microbiology. 2018. doi:10.1016/j.tim.2018.02.007Site-specific amino acid preferences are mostly conserved in two closely related protein homologs
Molecular biology and evolution. 2015. doi:10.1093/molbev/msv167An experimentally informed evolutionary model improves phylogenetic fit to divergent lactamase homologs
Molecular biology and evolution. 2014. doi:10.1093/molbev/msu220An experimentally determined evolutionary model dramatically improves phylogenetic fit
Molecular Biology and Evolution. 2014. doi:10.1093/molbev/msu173