Welcome to the Bloom Lab

where we study the evolution of Viruses

In the Bloom lab, we study the evolution of viruses and proteins. We use experimental and computational techniques to understand the molecular constraints on viral proteins, and how these constraints shape the capacity of viruses to evolve to escape antibodies, erode pre-existing immunity, and adapt to new hosts.

Our lab is part of the Basic Sciences Divison and the Computational Biology Program at the Fred Hutch. We are also affiliated with the Genome Sciences and Microbiology Departments at the University of Washington, and graduate students often join our lab through the MCB program. Jesse Bloom is an Investigator of the Howard Hughes Medical Institute.